Saint Joseph's Translational Research Institute

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Journal Club

Saint Joseph’s Translational Research Institute is pleased to announce the addition of the SJTRI Journal Club to the SJHA campus. Our move of the journal club seminar venue over to the hospital represents an important bridge we are building form SJTRI Preclinical to SJTRI Clinical, Saint Joseph’s Hospital of Atlanta, and the Saint Joseph's Heart and Vascular Institute.

We encourage anyone who is interested in attending the seminars at the hospital to join us and discover how the biomedical scientific backgrounds of our research endeavors translate from the bench to the patient bedside. Additionally, assisting in translating how your day-to-day activities can help move medical science forward; we encourage attendees to approach any of the scientific staff with questions for discussion.

If you are interested in attending, please contact one of our schedulers to reserve a time at (678) 843-6501

Past Journal Clubs

April 2008

May
2008

06/25/08

Alternatives to Drug-Eluting Stents: Modifying Diseased Blood Vessels with Drug-Loaded Nanoparticles

Presenter: Dr. Keith Robinson

Associated Documents

Intramural Delivery of Rapamycin With Targeted Paramagnetic Nanoparticles Inhibits Stenosis After Balloon Injury

06/11/08

Potential Mechanisms of Endothelial Dysfunction

Presenter: Dr. Lakshmana Pendyala

Both sirolimus-coated and paclitaxel-coated stents showed long-term endothelium related vascular dysfunction detected in non-stented segments of the coronary artery. Although the precise mechanism of this distant vascular phenomenon was unknown it was presumed to be secondary to the presence of either the antiproliferative drug itself or its associated polymeric DES coating. In this presentation we will review and discuss some the recent articles in the literature with a focus on the underlying mechanisms of endothelial dysfunction associated with drug-eluting stents.

Associated Documents

Sirolimus-Induced Vascular Dysfunction

06/04/08

A new-developed, single, expandable MESH catheter capable of both mapping and RF current delivery was introduced for circumferential pulmonary vein antrum isolation from canine left atrium.

Presenter: Dr. Hong Zeng

Current approaches utilized for PV mapping and ablation for AF treatment require multielectrode catheters or sophisticated advanced mapping system. Investigational devices utilizing other energy sources including ultrasound, laser, and cryo have been used to simplify PV electrical isolation procedures. These devices were not designed for mapping and an additional catheter is required to evaluate for PV isolation. A newly-developed, single MESH catheter capable of both high-resolution recording and RF current delivery will be introduced in this week’s Journal Club for circumferential pulmonary vein antrum isolation.

Associated Documents

A Novel Mesh Electrode Catheter for Mapping
and Radiofrequency Delivery at the Left Atrium-Pulmonary
Vein Junction: A Single-Catheter Approach to Pulmonary Vein
Antrum Isolation

Physician News

Press Release

Journal Club

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Saint Joseph's Translational Research Institute
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